Prime Day supplement deals: discounts on health-boosting vitamins and muscle-building protein

With these Prime Day supplement deals, you can stock up on vitamins and protein without breaking the bank

Two people taking supplements at home
(Image credit: Getty Images)

You can use this year's Prime Day supplement deals to pick up some of the top nutritional supplements, vitamins, and protein powders to help you look after your body and protect your mind at a significant discount.

Whether you're after omega-3 capsules, vitamin D or B12, or the best supplements for joints, Amazon cuts the price of many supplements across the two-day Prime Day event, which will take place on July 12th and 13th, 2022.

Fortunately, we've rounded up some of the best early Prime Day supplement deals available right now. So, you don't need to wait until the event itself to pick up some top supplements, including the best protein powder for weight loss, without breaking the bank.

We'll regularly update this guide as more deals become available in the days and weeks before this year's Prime Day sale. But before we add products in, we also check the prices to make sure you really are getting a money-save Prime Day supplement deal.

Prime Day supplement deals: US quick links

Prime Day supplement deals: UK quick links

Early US Prime Day supplement deals

NOW Supplements, Probiotic-10, 25 Billion | Was $49.99, now $24.99 at Amazon (opens in new tab)

Save 50% on one of the top gut health supplements right now. These 100 unflavored capsules are vegetarian and gluten-free, contain 10 probiotic strains, and support your digestive system.

Vitamin B12 by Nature's Bounty, 100mcg | Was $19.99, now $9.44 at Amazon (opens in new tab)

This 200-pack of vitamin B12 supplements can pick up where your diet leaves off. If you're vegan or eat a plant-based diet, these can help you stay topped up without meat. Save 51% on these supplements today.

Solgar Triple Strength Omega-3, 950 mg | Was $20.93, now $18.53 at Amazon (opens in new tab)

Protect your brain, look after your heart, and reduce inflammation with this omega-3 supplement. It comes with 50 soft gel capsules with 950mg of omega-3 in each. Save 11% on this top fish oil supplement right now.

NOW Supplements Vitamin D-3 | Was $22.99, now $11.75 at Amazon (opens in new tab)

If you find it hard to get out in the sun each day, these vitamin D supplements will help you stay topped up. These 240 soft gel capsules help support your immune system and boost wellbeing for almost 50% less.

Optimum Nutrition Gold Standard 100% Whey Protein Powder | Was $35.99, now $30.99 at Amazon (opens in new tab)

Build muscle for less with this high-quality protein powder. It comes in six flavors, including Cookies & Cream and Vanilla Ice Cream, and has 24g of whey protein per serving. Take advantage of the 15% discount before the deal ends.

MAV Nutrition Fish Oil Lemon Flavor Soft Gels | Was $39.99, now $22.49 at Amazon (opens in new tab)

These easy-swallow soft gels are packed with omega-3 to protect your body and promote wellbeing. There are 120 lemon-flavored capsules in a pack, which will last you 40 days. Save an incredible 44% before the deal ends.

Mary Ruth's Vegan B Complex Drops | Was $33, now $27.95 at Amazon (opens in new tab)

If you want to top up your vitamin B levels without taking capsules each day, these vegan-friendly drops are an excellent alternative. You can add the cherry-flavored drops to smoothies, shakes, or meals. Don't miss out on this 15% discount on a two-month supply.

Freshfield Vegan Omega 3 | Was $35.99, now $20.39 at Amazon (opens in new tab)

Omega-3 is often found in fish oils, but this plant-based supplement is a vegan-friendly way to get your daily dose. This pack contains a two-month supply of soft capsules and is now 43% less until the deal ends.

California Gold Nutrition Vitamin D3 | Was $13.60, now $1 at iHerb (opens in new tab)

Save an incredible 93% on this 360-pack of health-boosting vitamin D. The soft gel capsules are easy to swallow and contain 125mcg of the vitamin. Take advantage of this massive discount before the sale ends to get a year's supply for $1.

Early UK Prime Day supplement deals

Seven Seas JointCare Max | Was £22.72, now £13.94 at Amazon (opens in new tab)

Reduce inflammation and pain with this joint-friendly supplement. There are 60 capsules packed with omega-3, vitamin D, vitamin C, zinc, and collagen to protect and support your body; now, 39% off until the discount ends.

Bulk Natural Pure Whey Protein Concentrate | Was £18.99, now £15 at Amazon UK (opens in new tab)

This high-quality whey protein comes in Chocolate or Strawberry flavors and has 22g of protein per serving, with just 2g of carbs and 2g of fats. The dairy-based supplement has just seven ingredients, and right now, you can save 21% on this 500g back of muscle-building powder.

Prime Day supplement deals: when do sales start?

Amazon Prime Day will happen in July 2022, back to its original mid-year slot following adjustments in 2020 and 2021 due to the pandemic. Although we don't know the exact date yet, we expect deals to be released a couple of weeks earlier too.

That doesn't mean you need to wait until the event itself to find great deals on supplements. Amazon regularly offers discounts on some of the top supplements, including the best supplements for joints, and we've collected together money-saving deals you can use right now.

Amazon first launched Prime Day in 2015 for Prime subscribers to shop with exclusive discounts on a range of products for a single day. For the third annual shopping event in 2017, Amazon extended Prime Day across two days in July.

The yearly two-day event continued until 2020, when the COVID-19 pandemic affected businesses and supply chains worldwide. In that year, Amazon shifted Prime Day to October and then held the 2021 event in June.

Prime Day supplement deals: what to look out for

While you can get most nutrients from your diet, it's not always possible to get everything your body needs from food alone. If you can't add oily fish to your diet, there are so many benefits of fish oil that it's a good idea to use Prime Day to stock up on these omega-3 supplements. 

Similarly, if you eat a primarily plant-based or vegan diet, you may want to supplement your diet with vitamin B12, typically found in meat and other animal products. Our needs change over the years, so it's worth using supplements as you age, too but always seek advice from your doctor before taking a new supplement.

There may be discounts or savings on the best menopause supplements to help you manage hot flushes, mood swings, and night sweats as you go through menopause, while the best protein powder for women supports muscle growth and maintenance. 

When you exercise, small tears appear in your muscle fibers. Your body uses protein to repair these, and protein powders are a great way to ensure your muscles get everything they need to promote recovery and encourage muscle growth.

What makes a good Prime Day supplement deal?

To get the most from Prime Day supplement deals, it's worth considering what type of supplement would best support your body. If you're unsure, talk to your doctor or healthcare provider about your specific needs.

Supplements are usually branded or marketed towards certain lifestyles. These might be just what you need, but if you're after a vitamin D supplement, you might not need a more comprehensive multi-vitamin.

If you eat a vegan diet, then fish oil supplements and B12 vitamins are a good way to top up your nutrient levels, but be sure to look out for brands that specifically mention that they are vegan-friendly, as not all supplements are.

When searching for a Prime Day supplement deal, price is often a significant consideration. Before we feature any deals, we investigate historical prices, compare them against other retailers, and put them into context so you can make an informed choice.

James is a London-based journalist and Staff Writer at Fit&Well. He has over five years experience in fitness tech, including time spent as the Buyer’s Guide Editor and Staff Writer at technology publication MakeUseOf. In 2014 he was diagnosed with a chronic health condition, which spurred his interest in health, fitness, and lifestyle management.


In the years since, he has become a devoted meditator, experimented with workout styles and exercises, and used various gadgets to monitor his health. In recent times, James has been absorbed by the intersection between mental health, fitness, sustainability, and environmentalism. When not concerning himself with health and technology, James can be found excitedly checking out each week’s New Music Friday releases.