The best Prime Day supplement deals to shop in October
There are discounts on probiotics, vitamins, protein powders and more thanks to Amazon Prime's Big Deal Days


If you can't get sufficient vitamins and minerals through your diet alone, then supplements are a great option. Plenty of people use these tablets, powders and gels to make sure they're hitting their recommended daily dosage.
It can be pricey to stock up on these supplements, but luckily Amazon's October sales event (which is officially called Big Deal Days) has arrived and brought plenty of discounts with it. I've trawled through the sales to find the best savings and rounded them up below.
You need to be a Prime member to access some of these deals, but the good news is you can get a 30-day free trial on the platform, and cancel when the sales have ended.
Quick links
- Amazon: Huge discounts on best-selling supplements
- Target: Great deals on a wide range of supplements
- Walmart: See all vitamin and supplement deals
- MyProtein: Get up to 50% off protein powder
My US Amazon picks
These are the best Prime Day supplement deals you can buy in October.
- Mason Natural daily multivitamin: 20% off this vegan-friendly multivitamin ($6.36)
- Magnesium: Over 50% off from Nature's Bounty ($7.10)
- Probiotic: Amazon Basics probiotics are now as cheap as $10.27
- B12: These Nature Made Vitamin B12 softgels are just $9.48 (a 60% reduction)
- Melatonin: Save 56% on these sleep-promoting Natrol Melatonin 5mg ($9.59)
- Vitamin D: Grab these sugar-free Vitamin D3 gummies for $8.69 (54% cheaper)
- Protein powder: Popular Optimum Nutrition flavors are 40% cheaper on Amazon
- Whey isolate: 36% off Sports Research chocolate flavored protein powder
Prime Day US supplement deals
Prime Day protein powder deals
FAQs
When is the next Prime Day and is it only once a year?
Amazon's summer Prime Day event started on Tuesday, July 16th, and drew to a close at midnight the following day. But Amazon's second sales event (called Big Deals Day) is happening right now and will run from October 8th to October 9th.
While it's unlikely that Amazon will hold another special sales event this year, they will undoubtedly be taking part in Black Friday on November 29th.
Is it worth buying supplements during Prime Day?
While you should aim to get most, if not all, nutrients from your diet, it's not always possible to get everything your body needs from food alone and supplements can help address vitamin deficiencies.
If you eat a primarily plant-based or vegan diet, you may want to supplement your diet with vitamin B12, typically found in meat and other animal products. If you don't get enough exposure to sunlight, you might want to top up your vitamin D intake.
Our needs change over the years, so it's worth using supplements as you age too, but always seek advice from your doctor before taking a new supplement.
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Ruth Gaukrodger is the fitness editor for Fit&Well, responsible for editing articles on everything from fitness trackers to walking shoes. A lot of her time is spent interviewing coaches and fitness experts, getting tips on how to make exercise less intimidating and more accessible.
She's a keen runner and loves strength training. She also enjoys honing her yoga skills from the comfort of her living room.
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