Can Vitamin D help with inflammation? Here’s what science has to say

Recent research reveals how vitamin D can be used to help treat inflammation related to the Covid-19 virus

Person is pouring Vitamin tablets onto their hand
(Image credit: Getty)

Inflammation is your immune system’s response to injury or infection. While inflammation can be a force for good it can also be detrimental if more serious diseases, such as Covid trigger a more aggressive immune response. A recent study has discovered a link between vitamin D and its potential to reduce inflammation associated with Covid-19 responses.

Vitamin D has a good reputation in the health sphere already. It can be found in various foods such as oily fish, mushrooms, and egg yolks and it can also be consumed in a tablet form. Things like the best vitamins for women over 50 or the best fish oil supplements are a great option for people to top up on plenty of beneficial vitamins in addition to a nutritious diet.  

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 What have science discovered about vitamin D? 

A joint study (opens in new tab) jointly published by the National Institutes of Health and Purdue University found from analyzing the lung cells of eight different people with COVID that that immune response can go into overdrive. This significantly increased lung inflammation among the patients with COVID. 

Co-leader of the study, Majid Kazemian, and assistant professor in the departments of Computer Science and Biochemistry at Purdue University explained that inflammation can be caused by T cells. T cells are important to the immune system and are involved with how the immune system responds to COVID.

Kazemian said, "In normal infections, Th1 cells, a subset of T cells, go through a pro-inflammatory phase. The pro-inflammatory phase clears the infection, and then the system shuts down and goes to anti-inflammatory phase. 

“Vitamin D helps to speed up this transition from pro-inflammatory to the anti-inflammatory phase of the T cells,” he concluded.

Kazemian highlights that they used a special concentrated version of Vitamin D for the study and that drugstore vitamin D is not the answer to avoiding or treating Covid. 

Nutritionist, Dr Pamela Mason from the Health & Food Supplements Service told Fit&Well that Vitamin D also inhibits the production and development of pro-inflammatory body cells. 

She explained that receptors for vitamin D are found on many body cells including immune function cells and cells involved in inflammation. Cells involved in immune function and inflammation drive several chronic inflammatory diseases such as infection, cardiovascular disease, type 2 diabetes, cancer, and musculo-skeletal conditions. 

Therefore, Vitamin D can help to maintain overall health by regulating inflammatory processes. Getting outside into natural sunlight (in a pair of best shoes for walking) is a natural way of receiving your daily vitamin D.

Jessica is Staff Writer at Fit&Well. Her career in journalism began in local news and she holds a Masters in journalism. Jessica has previously written for Runners World, penning news and features on fitness, sportswear and nutrition. 


When she isn't writing up news and features for Fit&Well covering topics ranging from muscle building, to yoga, to female health and so on, she will be outdoors somewhere, testing out the latest fitness equipment and accessories to help others find top products for their own fitness journeys. Her testing pairs up nicely with her love for running. She recently branched out to running 10Ks and is trying to improve her time before moving on to larger races. Jessica also enjoys building on her strength in the gym and is a believer in health and wellness beginning in the kitchen. She shares all of this on her running Instagram account @jessrunshere which she uses for accountability and for connecting with like-minded fitness lovers.